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Matthew Perry’s official cause of death has been announced.  The actor died from “the acute effects of ketamine,” a drug that is used to treat depression and is also used as a recreational drug.

The Los Angeles County Medical Examiner’s Office concluded that Perry had ketamine infusion therapy for depression and anxiety a week-and-a-half before his death.

The K in his system at the time of his death, however, “could not be from that infusion therapy, since ketamine’s half-life is 3 to 4 hours or less.”

There was no evidence of alcohol, methamphetamine, cocaine, heroin, PCP, or fentanyl.

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